yeast artificial chromosome (YAC)
A vector constructed from the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells used to clone pieces of DNA c.
defined: Extremely large segments of DNA from another species spliced into DNA of yeast. YACs are used to clone up to one million bases of foreign DNA into a host cell, where the DNA is propagated along with the yeast cell's other chromosomes. explained: Listen to a detailed explanation. Dr. Eric Green, of the National Human Genome Research Institute's Genome Technology Branch, defines yeast artificial chromosome (YAC). related terms:  base pair, chromosome, cloning, deoxyribonucleic acid (DNA), Human Genome Project
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